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Jane B Lian Selected Research

Cleidocranial Dysplasia (Cleidocranial Dysostosis)

5/2010The cleidocranial dysplasia-related R131G mutation in the Runt-related transcription factor RUNX2 disrupts binding to DNA but not CBF-beta.
2/2009A Runx2 threshold for the cleidocranial dysplasia phenotype.
4/2006Four novel RUNX2 mutations including a splice donor site result in the cleidocranial dysplasia phenotype.
12/2002Cbfbeta interacts with Runx2 and has a critical role in bone development.

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Jane B Lian Research Topics

Disease

73Neoplasms (Cancer)
10/2020 - 02/2003
29Breast Neoplasms (Breast Cancer)
10/2020 - 05/2003
19Neoplasm Metastasis (Metastasis)
01/2020 - 05/2003
13Prostatic Neoplasms (Prostate Cancer)
01/2018 - 10/2005
11Carcinogenesis
01/2018 - 01/2005
11Leukemia
06/2017 - 11/2002
9Osteosarcoma (Osteogenic Sarcoma)
12/2014 - 04/2003
7Bone Diseases (Bone Disease)
11/2016 - 01/2011
6Osteolysis
11/2016 - 02/2005
6Genetic Translocation (Chromosomal Translocation)
04/2015 - 05/2005
6Bone Resorption
04/2015 - 03/2008
6Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
09/2012 - 11/2002
5Hypersensitivity (Allergy)
01/2017 - 08/2006
4Cleidocranial Dysplasia (Cleidocranial Dysostosis)
05/2010 - 12/2002
3Genomic Instability
01/2018 - 07/2014
3Adenocarcinoma
10/2016 - 01/2010
3Inflammation (Inflammations)
05/2016 - 01/2012
3Osteoporosis
06/2013 - 03/2008
3Metabolic Bone Diseases (Osteopenia)
12/2010 - 08/2008
3MASS syndrome
07/2009 - 09/2005
2Triple Negative Breast Neoplasms
06/2016 - 11/2015
2Multiple Myeloma
10/2010 - 02/2008
2Necrosis
10/2010 - 08/2003
2Arthritis (Polyarthritis)
03/2008 - 08/2003
1Fetal Alcohol Spectrum Disorders
01/2020
1Disease Progression
01/2018
1Rheumatoid Arthritis
03/2017
1Drug-Related Side Effects and Adverse Reactions
01/2017
1Hyperplasia
10/2016

Drug/Important Bio-Agent (IBA)

44Transcription Factors (Transcription Factor)IBA
10/2020 - 12/2002
22Proteins (Proteins, Gene)FDA Link
01/2018 - 11/2002
19Biological ProductsIBA
01/2020 - 03/2003
13MicroRNAs (MicroRNA)IBA
01/2018 - 01/2012
11ChromatinIBA
02/2018 - 04/2003
8Histones (Histone)IBA
02/2018 - 11/2008
5RNA (Ribonucleic Acid)IBA
01/2020 - 12/2008
5Biomarkers (Surrogate Marker)IBA
01/2018 - 04/2012
5DNA (Deoxyribonucleic Acid)IBA
06/2017 - 02/2005
5WW Domain-Containing OxidoreductaseIBA
01/2011 - 03/2007
4Small Interfering RNA (siRNA)IBA
10/2014 - 02/2012
3Hormones (Hormone)IBA
01/2018 - 03/2010
3Untranslated RNA (Noncoding RNA)IBA
01/2018 - 11/2013
3Adenosine Triphosphatases (ATPase)IBA
01/2018 - 11/2015
3EnzymesIBA
01/2017 - 11/2015
3Parathyroid Hormone-Related ProteinIBA
11/2016 - 12/2010
3Pharmaceutical PreparationsIBA
12/2014 - 12/2006
3IntegrinsIBA
03/2014 - 08/2009
3Core Binding Factor Alpha 1 SubunitIBA
02/2013 - 12/2009
3WD repeat containing planar cell polarity effectorIBA
05/2012 - 07/2006
3Transforming Growth Factor beta (TGF-beta)IBA
01/2012 - 10/2008
2Transfer RNA (tRNA)IBA
01/2020 - 01/2017
2AdiponectinIBA
01/2020 - 05/2016
2Long Noncoding RNAIBA
02/2018 - 01/2018
2Phenobarbital (Luminal)FDA Link
02/2018 - 11/2016
2Thyroid Hormone Receptors (Thyroid Hormone Receptor)IBA
01/2018 - 01/2016
2Deoxyribonucleases (DNase)FDA Link
01/2017 - 10/2014
2Integrin-Binding SialoproteinIBA
11/2016 - 05/2003
2CytokinesIBA
11/2016 - 09/2015
2OsteopontinIBA
11/2016 - 12/2010
2Androgen Receptors (Androgen Receptor)IBA
10/2016 - 03/2014
2A-factor (Streptomyces)IBA
05/2016 - 01/2012
2Interleukin-11 (Interleukin 11)IBA
09/2015 - 04/2015
2SurvivinIBA
01/2015 - 09/2009
2CateninsIBA
02/2013 - 05/2012
2Histone Deacetylase InhibitorsIBA
05/2011 - 12/2010
2Bortezomib (Velcade)FDA Link
10/2010 - 02/2008
2Proteasome Endopeptidase Complex (Proteasome)IBA
10/2010 - 12/2009
2Proteasome InhibitorsIBA
10/2010 - 02/2008
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
03/2010 - 01/2010
2SteroidsIBA
03/2010 - 06/2009
2NocodazoleIBA
12/2009 - 12/2006
2Protein Isoforms (Isoforms)IBA
06/2009 - 05/2003
2AcidsIBA
03/2008 - 08/2003
2CannabinoidsIBA
03/2008 - 08/2003
2lenabasum (ajulemic acid)IBA
03/2008 - 08/2003
2Paclitaxel (Taxol)FDA LinkGeneric
12/2006 - 02/2006
2OsteocalcinIBA
09/2005 - 04/2003
1PPAR gammaIBA
01/2020
1Sterol Regulatory Element Binding ProteinsIBA
01/2020
1Fatty Acid-Binding ProteinsIBA
01/2020
1Coenzyme A (CoA)IBA
01/2020
1Core Binding Factor Alpha 2 SubunitIBA
01/2020
1Acetyl-CoA CarboxylaseIBA
01/2020
1LeptinIBA
01/2020
1Lipoproteins (Lipoprotein)IBA
01/2020
1Thyroid HormonesIBA
01/2020
1Circulating MicroRNAIBA
01/2019
1Antisense RNA (Anti-Sense RNA)IBA
02/2018
1Prostate-Specific Antigen (Semenogelase)IBA
01/2018
1Silicon Dioxide (Silica)FDA LinkGeneric
01/2018
13' Untranslated Regions (3' UTR)IBA
06/2017
1Co-Repressor ProteinsIBA
06/2017
1Indicators and Reagents (Reagents)IBA
03/2017
1Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
01/2017
1Serotonin (5 Hydroxytryptamine)IBA
01/2017
1Fatty Acids (Saturated Fatty Acids)IBA
06/2016

Therapy/Procedure

20Therapeutics
10/2020 - 03/2008
4Drug Therapy (Chemotherapy)
01/2018 - 02/2006
2Oral Administration
03/2008 - 08/2003
1Chemoprevention
01/2019